COMETS is a software platform for performing computer simulations of metabolism in spatially structured microbial communities. It is based on stoichiometric modeling of the genome-scale metabolic network of individual microbial species (using dynamic flux balance analysis), and on a discrete approximation of convection-diffusion equations.
The first version of COMETS became publicly available in 2014, and was associated with the following paper: Harcombe et al., Metabolic Resource Allocation in Individual Microbes Determines Ecosystem Interactions and Spatial Dynamics, Cell Reports, 2014.
COMETS in journal articles:
Cell Report, 2014
PLOS Biology 2016
ISME Journal, 2018
Biomedical Physics And Engineering Express, 2018